BIOL 54400 - Principles Of Virology

This is an intensive upper-division course focused on the molecular biology of viruses and eukaryotic cells. Students will learn about the genetic and molecular structure of viruses, their replication and modes of infection. Viral RNA, DNA and protein synthesis will be discussed in detail. Intracellular trafficking, assembly and exit of viral particles will be studied. HIV pathogenesis and oncogenesis by viruses will get special emphasis along with vaccines and antiviral drugs. Molecular biological insights gained by study of viruses will be discussed in detail.

Preparation for Course
P: BIOL 21800 and 38100 with grades of C- or better.

Cr. 3.
Student Learning Outcomes
1. Define a virus and describe the structure of viruses.
2. Outline the molecular basis of viral classification.
3. Explain the mechanism of viral attachment and entry into host cells.
4. Describe the processes used by viruses in replicating their genomes.
5. Explain how viruses control protein synthesis and intracellular trafficking inside cells.
6. Describe AIDS, cancer, coronavirus disease from the viral perspective.
7. Outline the vaccines and antiviral therapies currently available.